The Serpentone
Weird Universe

There’s not a lot of information online about this unusual instrument, the Serpentone, and much of it is in Italian. Italian wikipedia (via google translate) tells us that it was invented in the sixteenth century and was “used as a low to accompany choirs and chamber music.”
Italian wikipedia also tells us that the Serpentone, “is considered the most difficult of instruments, which are part of the family of brass, but, for this reason, perhaps one of the most fascinating.”